Johnny Test concerns the adventures of Johnny Test, an average 11-year-old boy who lives in Porkbelly. Johnny is the troublesome, narcissistic, spoiled and widely disrespected member of the Test family, which consists of his super-genius 13-year-old twin sisters, Susan and Mary, his talking (and talkative) companion dog, Dukey, and his over-the-top parents, his mother Lila, who is a full-blown workaholic businesswoman, and his father Hugh, who is a obsessive-compulsive househusband who likes total hygiene and meatloaf. The Test twins use their younger brother as a guinea pig for their various experiments (thus their surname of Test) in their secret laboratory, with which they try to impress Gil Nexdor, their pretty boy next-door neighbor.